经皮冠状动脉腔内成形术对冠心病患者QT间期离散度的影响(摘要)

中国循环杂志 1999年第0期第14卷 摘要　冠心病介入治疗

作者：赵安乐　心内科　齐国先　曾定尹

单位：辽宁省，营口市中心医院　心内科(115002)　赵安乐； 中国医科大学附属一院　心内科　齐国先　曾定尹

　　目的：QT间期离散度对心肌缺血和冠状动脉狭窄的严重程度具有预测价值，本研究目的在评价经皮冠状动脉腔内成形术(PTCA)对冠心病患者QT间期离散度的影响。

　　方法：26例成功地行PTCA的冠心病患者，男21例、女5例，平均年龄56.5±10.1岁，单支血管病变13例，双支血管病变9例，三支血管病变4例，本研究对PTCA术前后12导联心电图QT间期离散度(QTd)及校正后QTd(QTcd)进行测定。

　　结果：术后QTd及QTcd均有明显减少(P＜0.01),QTd从69.5±26.8 ms减少至34.3±13.7 ms(P＜0.01),QTcd则从74.1±30.1 ms减少至28.3±10.3 ms(P＜0.01)。

　　结论：冠心病患者QTd及QTcd在PTCA术后随着心肌缺血及心室复极不均一性的改善而降低。

Effects of Percutaneous Transluminal Coronary Angioplasty on QT Dispersion in Patients with Coronary Artery Disease (Abstract)

Department of Cardiology, central Hospital of Yingkou (115002), Liaoning

　　Zhao Anle, Qi Guoxian, Zeng Dingyin.

　　Objective: QT dispersion (QTd) has a predictive value for the presence of myocardial ischemia and the order of severity of coronary artery stenosis. The purpose of this study was to assess the effects of percutaneous transluminal coronary angioplasty (PTCA) on QTd in patients with coronary artery disease.

　　Methods: PTCA was performed successfully on 25 patients with coronary artery disease, 21 men and 5 women, mean age 56.5±10.1 years. QTd and QTcd (corrected QTd) were obtained with a standard 12-lead ECG before and after PTCA.

　　Results: The results showed that QTd and QTcd after PTCA were reduced significantly compared with those before PTCA. QTd decreased from 69.5±26.8 ms to 34.3±13.7 ms (p＜0.01), and QTcd from 74.1±30.1 ms to 28.3±10.3 ms (p＜0.01).

　　Conclusion: QTd and QTcd were decreased significantly after PTCA due to the improvement of myocardial ischemia and hoterogeneous repolarization in patients with coronary artery disease.