1.Li WH, Tanzmura M, Luo CC, etal Datta, S,and Chan L, The apolipioprotein multigene family:biosynthesis,structue,structure-function relationships, and evolution.J LipidRes,1988,29:245-271
2.Chan,L,The,apolipoproteinmultigene family: structure,express evolution and moleculargenetics.Kin.Wochenschr,1986,67:225-237
3. Young S G.Recent progress inunderstanding apolipoprotein B.Circulation,1990,82:1574-1594
4.Mclean JW ,Tomlinson JE,KuangWJ,et al cDNA sequence of hunan apoliporpotein(a) is homologous toplasminogen.Nure 1987,330:132-137
5. Ichinosie A.Multiple membersof the plasminogen,apolipoprotein(a) gene family associated withthromboses.Biochemistry 1992,31:3113-3118
6.Shoulders CC,KornblihttAR,Munro BS,et al Gene structure of human apolipoprotein AI.Nucleic AcidRes,1983,88;2827-2837
7. Tsao YK,Wei CF,Robberson DL,etal.Isolation and chraacterization of the human apolipoprotein AⅡgene.Electronmicrosscoic analysis of RNA:DNA hybrids,nucleotide sequence ,identification ofa polymorphic MspI site and general structural organization of apolipoproteingenes J Biol Chem,1985,260:15222-15231
8. Karathanasis SK,YunisI,Zannis,VI.Structure,evolution and tissue apecific synthesis of humanapolipoprotein AIV.Bochem,1986,25:3962-3970.
9.Blackhart BD,Ludwlg EM,PierottiVR,et al Structure of the Human apolipoprtein B gene.j BiolChem,1986,261:15264-3970
10. Knott TJ,RobertsonME,Priestley LM,et.al Characterization of mRNAs encoding the precursor forhuman apoliporpotein CI.Nucleic Acid Res,1984,12:3909-3915
11. Wei CF,Tsao YK,RobbersonDL,et al.The structure of the human apolipopretinCⅡ gene.Electron microscopicanalysis of RNA:DNA hybrids complete nucleotide sequence and identification of5’homologous sequences among apolipoprotein genes J BiolChem.1985,260:15211-15221
12.a Protter AA,Levy WilsonB,Miller J,et al Isolation and sequence analysis of the human apolipoproteinC-Ⅲgene an dthe intergenic region between AopAI and ApoC-Ⅲ genes and theintergenic region between ApoAI and ApoC-Ⅲ genes..DNA,1984,3:449-456
13.b Allan CM,Wallker D,SegrestJP,et al Identification and characterization of a new human gene (APOC-Ⅳ)in theapolipoprotein E,C-I,and C-Ⅱgene locus .Genomics ,1995,28291-300
14.Drayna DT,McLean JW,Wion KL,etal Human apolipoprotein Dgene:gene sequence,chromosome localization andhomology to the ? globulin –globulin superfamily ,DNA,1987,6:199-124
15.Das HK,McPherson J,BrunsGAP,et al.Isolation and characterzation and mapping to chromosome 19 of thehuman apolipoprotein E.Cene,J Biol Chem,1985,260:6240-6247
16. Day JR,Albers JJ,GilbertTL,et al Purification and molecular cloning of human apolipoprotein F.BiochoimBiophgys Res Commun,1994,203:1146-1151
17. Steinkasser A,EstallerC,Weiss EH,et al Complete nucleotide and deduced amion acid sequence of human humanβ2-glycoprotein I.Biochem J,1991,227:387
18.De Silva HV,Harmony JAK,StuartWD,et al Apolipoprotein J:struture and tissue distrbutionBiochem,1990,29:5380-5389
19.Kao FT,Chan L.Ghromosomal finemapping of apolipoprotein genes in the human genome by somatic cell hybridsMethods Enzymol,1986,128:851-863
20.Harper ME,Chan L,Chromosomalfine mapping of apolipoprotein genes by in situmucleic acid hybridization tometaphase chromosomes Metthods Enzymol,1986,128:863-786
21. Karathanasis SK .Apolipoproteinmutligene family and tandem organization of human apolipoprtein A-I,C-Ⅲ and A-Ⅳgenes .Proc Natl Acad Sci USA,1985,82:6374-6378
22.Lusis AJ,Heinzmann C,SparkesRS,et al.Regional mappoing of human chromosome 19:organization of genes forplasma lipid transport(APOC1,-C2,and-E and LDLR)and the genes C3,PEPD,andGPI.Proc Nat Acad Sci USA ,1986,83:3929-3933
23. Spardes RS.Winokur S,LusisAJ,et al Regional assignment of the apolipoprotein A I gene by in situhybridization to human chromosome iiq-qter.Cytogenet Cell Genet,1987,46:697
24 .Middleton-Price HR,VandenBerghe JA,Scott J,et al.Regional chromosomal localisation of ApoAⅡ tolq21-lq23.Hum Genet,1988,79:283-285
25. Law SW,Lee N,Monge JC et alHuman ApoB100 gene resides in the P23→pter region of chromosome 2.BiochimBiophys Res Commun,1985,131:1003-1012
26. Olaisen B,TeisbergP,Gedde-Dahl T,et al. The apolipoprotein E(ApoE)locus on human chromosome19.Cytogenet Cell Genet,1984,37:559
27. Steindasserer A,CockbarnDJ,Black DM,et al.Assignment of apolipoprtoein H(ApoH:beta-2glycoprotein I)tohuman chromososme 17q23→qter;determination of the major expression siteCytogenet Cell Genet .1992,60:31-33
28. Fink TM.Zimmer M.Tschopp J,etal Human chusterin(CLI)maps to 8p21 in proximity to the lipoproteinlipase(LPL)gene.Genomics,1993,16:526-528
29. Walden CC,HegeleRA.Apolipoprotein E in Hyperlipdemia Am Intem Med,1994,120:1026-1036
30.Kane JP,Havi RJ.Disorders ofthe biogenesis and secretion of lipoproteins containing the B apoliprproteinsIn:The metabolic and molecular bases of inherited disease edsScriver,C,R,Bearder AL,Sly W S,and Valle D,7thedition,Voll,1995,1583-1885,McGraw-Hill,Inc, New York,U.S.A
31.Brom MS,Goldstein JL,Areceptor-mediated pathway for cholesterol homeostasis ,Science,1986,232:34-47
32. Soria LF,Ludwig EH,ClarkeHRG,et al.Association between a specific apolipoprtein B mutation and familialdefective apolipoprotein B-100,Proc Natl Acad Sci USA,1989,86:587-591
33. Hegele RA,Huang LS,HerbertPN,et al Apolipoprotein B gene DNA polymorphipms associated with myocardialinfarction .N Engl j Med,1986,315:1509-1515
34.a.Visvik S,Cambou JP,ArveilerD et al.Apolipoprotein b signal peptide poly morphism in patients with myocardial infartions and controls, Hum Genet,1993,90:561-565
35.b.Kammerer CM,VandebergJL,Haffner SM,et al Apolipoprotein B(ApoB)signal peptide length polymorphismsare associated with ApoB.low density lipoprotein cholesterol and glucose levelsin mexican Americans.Atherosclerosis,1996,120:37-45
36.Kinjff PD,Van den MaagdenbergAMJM,Frants RR.et al Genetic heterogeneity of apolipoprotein Eand its influence on plasmea lipid and lipoprotein levels Hum Mutation,1994,4:178-194
37. Mahley RW,Stanley CrallJr,TypeⅢhyperlipoproteinemia(Dysbetalipoproteinemia)The role of apolipoproteinEin normal and abnormal ilpoprotein metabolism In:The metabolic and molecularbases of intherited disease,7thed eds Scriver C.R,Beaudet A L,Sly W S,and ValleD Vol Ⅱ,pp1953-1980,McGraw-Hill,Inc,New Your,1995
38.Rose AD Apolipoprotein Ealleles as risk factors in alzheimers disease .Am Rev Med ,1996,47:387-400
39.Utermann G,Menzel HJ,KraftHG,et al Lp(a) glycoprotein phenotypes ,Inheritance and relation toLp(a)lipoprotein concentrations in plasma.Jclin Invest.1987.80:458-465
40.Utermann G.Lipoprotein(a)In:The metabolic and molecular bases of inherited disease.7th ed ,Vol.Ⅱ,eds.Scriver C R.Beandet A L.Sly W.S,Valle,D.pp1887-1912,McGraw-Hill,Inc,NewYour,1995
41.Scanu AM,EdelsteinC.Kringle-dependent structural and functional polymorphism ofapolipoprotein(a).Biochim Biophys Acta,1995,1256:1-12
42. Mooser V,Mancini FP,Bopp S etal Sequence polymorphisms in the Apo(a)gene associated with specific levels ofLp(a)in plasma.Hum Mol Genet,1995,209:372-378
43.Ichinose A,KuriyamaM.Detection of polymorphisms in the 5’flanding region of the Gene forapolipoprotein(a),Biochim biophys Res Commam,1995,209:372-378
44. Breslow JL Apoipoproteingenes and atherosclerosis.Clin Investig,1992,70:377-384
45.Von eckardstein A,FunkeH.Walter M,et al.Structural analysis of human apolipoprotein AI variants JbiolChem,1990,265:8610-8617
46.Talmud PJ,Ye S.HumphriesSE,Polymorphism in the promotor region of the apolipoprotein AI gene associatedwith differences in apolipoprotein AI levels:The European AtherosclerosisResearch Study.Genet Epidemiol,1994,11:265-80
47.Saha N,Tay JS,Low PS,et alGuanidine to adenine(G/A)substitution in the promoter region of theapoliprotein AI gene is associated with elevated aerum apolipoprotein AI levelsin Chinese non-smoders Genet Epikemiol,1994,11:255-64
48.Wang XL.Badenhop R,HumphreyKE,et al.New Mspl polymorphism at +83 BP of the human apolipoprotein AIgene-Association with increased circulating high density lipoprotein cholesterollevels.Genet Epidemid,1996,13:1-10
49.Humphries SE.DNA polymorphismsof the apolipoprotein genes-their use in the investigation of the geneticcomponent of hyperlipidaemia and atherosclerosis.Atherosclerosis,1988,72:89-108
50.Dallinga-Thie GM,Bu XD,TripMV,LS,et al.Apolipoprotein A-Ⅰ/CⅢ/A-Ⅳgene cluster in familial combinedhyperlipidemia:effects on LDL-cholesterol and LDL-cholesterol andapoplipoproteins B and CⅢ,J Lipid Res,1996,37:136-147
51.Klasen EC,Talmud PJ,HavekesL,et al.A common restriction fragment length polymorphism of the humanapolipoprotein E gene and its relationship to type Ⅲ hyperlipidaemia HumGenet,1987,75:244-247
52.Deeb SS,Takata K,Peng RL,et alA splice-uunction mutation responsible for familial apolipoprotein A-Ⅱdeficiency Am J Hum genet,1990,46:822-827
53.Zaiou M,Visvidis S,GueguenR,et al DNA polymorphisms of human apolipoprotein A-Ⅲ gene frequency andeffects on lipid,lipoprotein and apolipoprtein lkevels in a French populationClin Genet.1994,46:248-254
54. Kamboh MI,Crawford MH,AstonCE Population distributions of ApoE,ApoH,and ApoaⅣ poly morphisms and theirrelationships with quantetative plasma lipid levels among the Evenki herders ofSiberia .Hum Biol,1996,68:231-243
55.Brunzell JD.Familialilpoprotein lipase deficiency and other carses of the chylomicronemia syndrome.In:Themetabolic and molemlar bases of inherited disease.7th ed ,Vol Ⅱ,edsScriver C R,Beandet A L,Sly W S,Valle D,pp1913-1932,McGraw-Hill,Inc,NewYourk,1995
56.Beheshti I,Hanson NQ,CopelandKB,et al. Single strand conformational polymorphisms(SSCP):Studies of thegenetic polymorphisms of exon4of apolipoprotein CⅢ,Clin Biochem,1995,28:303-307
57.li WW,Dammerman MM.Smith JD,etal Common genetic varation in the promotor of the human ApoCⅢ gene abolishesregulation by insulin and may contrbute to hypertriglyceridemia.J ClinInvest,1995,96:2601-2605
58.Vijayaraghavan S,HitmanGA,Kopelman PG,Apolipoprotein-d polymorphism:A genetic marker for obesity andhyperinsulinemia.J Clin Endocrinol Metab,1994,79:568-570
59.Roberts SB,Greenberg AS Thenew obesity genes .Nutrition Reviews ,1996,54:41-49
60.Steindasserer A,DornerC.Wurzner Ret al.Human β-glcoprotein Ⅰ:molecular analysis of DNA and amino acidpolymorphism.Hum Genet,1993,91:402-402
61.Kamboh MI,HarmoryJAK.Sepehrnia B,et al Genetic studies of human apolipoproteins XX.Geneticpolymorphism of apolipoprtein J and its impact on quantitative lipid traits innormolipidemic subjects Am J Hum Genet,1991,49:1167-1173